FlurBiprofen impurity 4
4-Acetyl-2-fluorobiphenyl
CAS: 42771-79-9
Molecular Formula: C14H11FO
FlurBiprofen impurity 4 - Names and Identifiers
FlurBiprofen impurity 4 - Physico-chemical Properties
| Molecular Formula | C14H11FO |
| Molar Mass | 214.23 |
| Density | 1.124±0.06 g/cm3(Predicted) |
| Melting Point | 94-95 °C |
| Boling Point | 321.8±22.0 °C(Predicted) |
| Physical and Chemical Properties | Chemical properties prismatic crystals (ethanol). Melting point 94-95 ℃. |
| Use | Uses Intermediate of flurbiprofen. |
FlurBiprofen impurity 4 - Production method
p-bromoacetophenone can be nitrated with mixed acid to generate 4-bromo-3-nitroacetophenone, and then condensed with iodobenzene under the catalysis of copper powder to generate 4-acetyl-2-nitrobiphenyl, the latter's nitro group is reduced to amino group, and then the product is prepared by fluorofluoric borofluoric acid.
Last Update：2024-04-09 01:59:51
FlurBiprofen impurity 4 - Introduction
It is an organic compound with the chemical formula C10H9FO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystal or crystalline powder with special smell.
-Melting point: about 84-86°C.
-Boiling point: approximately 297°C.
-Solubility: It is insoluble in water, but soluble in a variety of organic solvents, such as ethanol, benzene and carbon disulfide.
-Stability: It is relatively stable at room temperature, but flammable under high temperature, fire source and other conditions.
Use:
-It can be used as an intermediate in organic synthesis for the synthesis of other compounds.
-It can also be used in the pharmaceutical field as a raw material for some drugs.
Preparation Method: The preparation of
-fluorobiphenyl can be obtained by acetylation of 4-fluorobiphenyl. One method of preparation is to react 4-fluorobiphenyl with acetic acid at a certain temperature to produce bene.
Safety Information:
-layer on the eyes, skin and respiratory system irritation, should avoid contact.
-For safety reasons, you should wear appropriate protective equipment, such as gloves and protective glasses.
-During storage and handling, avoid contact with oxidants and fire sources to prevent combustion or explosion accidents.
-If you touch or inhale, wash the affected area immediately and seek medical help.
Please note that the specific use, preparation and safe handling of chemicals should be carried out under the guidance of professionals.
Nature:
-Appearance: White crystal or crystalline powder with special smell.
-Melting point: about 84-86°C.
-Boiling point: approximately 297°C.
-Solubility: It is insoluble in water, but soluble in a variety of organic solvents, such as ethanol, benzene and carbon disulfide.
-Stability: It is relatively stable at room temperature, but flammable under high temperature, fire source and other conditions.
Use:
-It can be used as an intermediate in organic synthesis for the synthesis of other compounds.
-It can also be used in the pharmaceutical field as a raw material for some drugs.
Preparation Method: The preparation of
-fluorobiphenyl can be obtained by acetylation of 4-fluorobiphenyl. One method of preparation is to react 4-fluorobiphenyl with acetic acid at a certain temperature to produce bene.
Safety Information:
-layer on the eyes, skin and respiratory system irritation, should avoid contact.
-For safety reasons, you should wear appropriate protective equipment, such as gloves and protective glasses.
-During storage and handling, avoid contact with oxidants and fire sources to prevent combustion or explosion accidents.
-If you touch or inhale, wash the affected area immediately and seek medical help.
Please note that the specific use, preparation and safe handling of chemicals should be carried out under the guidance of professionals.
Last Update：2024-04-09 15:16:22
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